SPOILER: GIRLFRIEND DO NOT READ FURTHER. DO NOT READ FURTHER!!!
I hope your girlfriend doesn't read my comments but one thing you should try is order some placebo pills, put them into very expensive looking packaging and then have you and doctors act like it is a very exclusive, super novel, zero risk druk, 100% success rate in animals
I know this is not what you seek. but this is ZERO risk, placebo WORKS in clinical studies, hopefully with her as well. basically make it a theater, make it the non-plus ultra treatment, the more doctors and nurses you can get into the act the better. The act surprised after only 2 days "WOW I've never seen this" etc
This article is more, not less, wrong. The placebo effect has nothing to do with drug pills vs sugar pills vs no pills. The pill is empty. The effect is not in the placebo pill; the effect is in the subject (belief/hope/care/oxytocin…)
Your event was the first time I said that I wanted to do this out loud. My inability to communicate it well then really pushed me to get better at telling our story!
Hi - You should contact the company AbSci and ask about compassionate use programs to use their anti-prolactin receptor antibody. They may not be able to give your girlfriend the drug yet, but if/when they do, it would likely cure or largely treat her symptoms if she takes is chronically and her tumor is purely driven by prolactin. https://www.absci.com/
I'm a patient with moderate-severe ME/CFS, meaning that I'm unable to work, see friends, or live independently. I spend a lot of time in bed in a darkened room. There's are no approved treatments, and no interest by pharma (because new indications carry to much regulatory risk to justify the cost). I'm very experimentally-minded, very AI-pilled, and can relate a lot to your story.
Different condition, same instinct. My wife has a multi-system chronic illness (Lyme, MCAS, autoimmune overlap) and the turning point wasn’t finding the right doctor, it was when I stopped waiting for someone else to connect the dots and started doing it myself. The journal entry before her surgery hit hard, I know that exact feeling of sitting somewhere useless while someone else’s hands hold your person’s future. Following this.
I think it’s when you start dealing with life and death that you get clarity on purpose. The other day, my friends and I were discussing what sectors of tech were most “noble” vs what makes money/is the best for your career, and it’s clear that we just need the best technologists working on seemingly impossible and underserved problems in healthcare like this one. In my opinion, nothing else really matters more, so thank you for being brave and embarking on this journey - wishing all the best for you and Amy.
Bone density lights up a red flag, you might want to look into the vitamin A toxicity angle (Grant Genereux). Just know that serum levels aren't at all a precise indicator.
very cool andrew. i lost my infant son to a rare, aggressive cancer last year, i related to a lot of this. excited to follow along and see what you’re able to do!
SPOILER: GIRLFRIEND DO NOT READ FURTHER. DO NOT READ FURTHER!!!
I hope your girlfriend doesn't read my comments but one thing you should try is order some placebo pills, put them into very expensive looking packaging and then have you and doctors act like it is a very exclusive, super novel, zero risk druk, 100% success rate in animals
I know this is not what you seek. but this is ZERO risk, placebo WORKS in clinical studies, hopefully with her as well. basically make it a theater, make it the non-plus ultra treatment, the more doctors and nurses you can get into the act the better. The act surprised after only 2 days "WOW I've never seen this" etc
https://youtube.com/watch?v=jryBmv0NpwA
https://youtube.com/watch?v=9LPR-Go8JWA
https://youtube.com/watch?v=XiWfb973YIk
It doesn't really work like that
https://www.lesswrong.com/posts/kpd83h5XHgWCxnv3h/why-i-don-t-believe-in-the-placebo-effect
This article is more, not less, wrong. The placebo effect has nothing to do with drug pills vs sugar pills vs no pills. The pill is empty. The effect is not in the placebo pill; the effect is in the subject (belief/hope/care/oxytocin…)
Right, the article is about how that effect (regardless of its source) is not actually strong. You can’t cure cancer with a placebo.
this is incredible - can’t wait to follow along 🫶
Thanks Annie! Your support means a ton :)
Your event was the first time I said that I wanted to do this out loud. My inability to communicate it well then really pushed me to get better at telling our story!
Beautiful story, I wish you the best!
Hi - You should contact the company AbSci and ask about compassionate use programs to use their anti-prolactin receptor antibody. They may not be able to give your girlfriend the drug yet, but if/when they do, it would likely cure or largely treat her symptoms if she takes is chronically and her tumor is purely driven by prolactin. https://www.absci.com/
I am praying for your success.
I'm a patient with moderate-severe ME/CFS, meaning that I'm unable to work, see friends, or live independently. I spend a lot of time in bed in a darkened room. There's are no approved treatments, and no interest by pharma (because new indications carry to much regulatory risk to justify the cost). I'm very experimentally-minded, very AI-pilled, and can relate a lot to your story.
Best of luck!
2026-02-06 19:42
https://www.youtube.com/results?search_query=thomas+setfried
Have you heard of Dr. Thomas Seyfried?
Some cancers can't use ketones for energy, so they starve.
https://www.youtube.com/results?search_query=thomas+setfried
Hope this helps...
Mike
Aurora, Colorado
Rooting for you and Amy 🙏
Thanks Alex! Btw, I loved your piece on statins last year :)
what a crazy story. wishing you both the best!!
Different condition, same instinct. My wife has a multi-system chronic illness (Lyme, MCAS, autoimmune overlap) and the turning point wasn’t finding the right doctor, it was when I stopped waiting for someone else to connect the dots and started doing it myself. The journal entry before her surgery hit hard, I know that exact feeling of sitting somewhere useless while someone else’s hands hold your person’s future. Following this.
Stay strong.
I'm only data engineer but I have a few AI analysts in environment. Best I can do is sharing it in tech. Fight hard bro!
I think it’s when you start dealing with life and death that you get clarity on purpose. The other day, my friends and I were discussing what sectors of tech were most “noble” vs what makes money/is the best for your career, and it’s clear that we just need the best technologists working on seemingly impossible and underserved problems in healthcare like this one. In my opinion, nothing else really matters more, so thank you for being brave and embarking on this journey - wishing all the best for you and Amy.
Incredible 💞
GOOD LUCK, Godspeed
Bone density lights up a red flag, you might want to look into the vitamin A toxicity angle (Grant Genereux). Just know that serum levels aren't at all a precise indicator.
Good luck!
very cool andrew. i lost my infant son to a rare, aggressive cancer last year, i related to a lot of this. excited to follow along and see what you’re able to do!